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Human Ovarian Fibroblasts | ||||
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| Product Name | Human Ovarian Fibroblasts | |||
| Price | Get Quote | |||
| Product Code | HOF | |||
| Cat.No | ABC-TC3741 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | Human Ovarian Fibroblasts are isolated from healthy human ovaries and serve crucial functions in tissue maintenance. They are responsible for synthesizing components of the extracellular matrix, supporting the structural integrity of connective tissues, and actively participating in wound healing processes. In the presence of ovarian cancer cells, these fibroblasts within the stroma undergo significant structural and biochemical changes. Ovarian cancer cells prompt normal ovarian fibroblasts to release a diverse range of peptides, including growth factors, chemokines, collagens, and matrix-modifying enzymes, creating a pro-tumorigenic and anti-immunogenic microenvironment that facilitates cancer progression and metastasis.
Why choose Human Ovarian Fibroblasts from AcceGen?
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| Disease | Normal | |||
| Source Organ | Ovarian | |||
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
| Recommended Medium And Supplement | ABM-TM3741 Human Ovarian Fibroblasts Medium Kit | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | FOR RESEARCH USE ONLY Human Ovarian Fibroblasts find valuable applications due to their stimulatory role in cancer development and invasive behavior. They serve as essential in vitro models for studying the pathophysiology of ovarian diseases, offering insights into disease mechanisms. Moreover, these fibroblasts prove to be indispensable tools for establishing in vitro disease models, enabling High Throughput and High Content Screening, thereby advancing research and potential therapeutic interventions. | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Fibroblast | |||
| Growth Mode | Adherent | |||
| Product Type | Female Reproductive Cells | |||
| Product Image |  | |||
AcceGen’s Human Ovarian Fibroblasts are cryopreserved at passage one, with each vial containing over 500,000 viable cells in 1mL volume. They exhibit spindle morphology and are fibronectin-positive. The cells are free from HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi, ensuring their safety. Additionally, they can undergo up to 15 population doublings as per provided instructions, making them an ideal tool for research and experimentation.- ONLINE INQUIRY
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