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Human Oral Epithelial Cells

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Product Name

Human Oral Epithelial Cells

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Cat.No

ABC-TC4365

Species

Human

Size/Quantity

1 vial

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The oral epithelium is a mucous layer in the mouth consisting of stratified squamous epithelial cells either keratinized or nonkeratinized. The oral epithelium and an underlying layer of lamina propria together form the mucosal epithelium that act as a physical barrier to external environment. For instance, the oral gingival epithelium act as a main barrier against bacterial biofilm that triggers gingivitis and periodontitis. Human primary oral epithelial cells are mainly distributed in the buccal part of oral cavity and undergoes continual regeneration to compensate for the damage caused by daily chewing.
Why Choose Human Oral Epithelial Cells from AcceGen?
Human oral epithelial cells from AcceGen are isolated from human oral mucosa. Human oral epithelial cells culture are cryopreserved at passage 3 in the media. Each vial contains > 5×10^5 cells in 1 ml volume. Antibodies specific to oral epithelial cells such as cytokeratin-18 are tested positive by immunofluorescence. Human oral epithelial cells can be further expanded for 2-4 passages at a split ratio of 1:2 or 1:3 under the condition and protocols recommended by AcceGen. All cells are tested negative for HIV-1, HBV, HCV and other pathogens.

Disease

Normal

Source Organ

Oral

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement

ABM-TM4365 Human Oral Epithelial Cells Medium Kit

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Shaikh, Sadiya Bi et al. “Flavor Classification/Categorization and Differential Toxicity of Oral Nicotine Pouches (ONPs) in Oral Gingival Epithelial Cells and Bronchial Epithelial Cells.” Toxics vol. 10,11 660. 31 Oct. 2022, doi:10.3390/toxics10110660

Application

For research use only
AcceGen human oral epithelial cells provide an excellent model for epithelial cell study and pharmacological testing. Due to its great regenerative capacity, primary normal oral epithelial cells can be employed to regenerative medicine and tissue engineering. These cells are also good cell source to study clinically relevant viral, bacterial, fungal, and autoimmune disease in oral cavity.

Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Oral Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial

Frequently Asked Questions

  • What are Human Oral Epithelial Cells, and how are they isolated?

    Human Oral Epithelial Cells are the cells that line the surface of the oral cavity. They are typically isolated from human oral mucosa tissue through enzymatic digestion followed by selective culturing.

  • What research applications are Human Oral Epithelial Cells used for?

    These cells are commonly used in studies of oral diseases, wound healing, cancer research, drug delivery systems, and the effects of various oral care products.

  • What are the ideal storage conditions for Human Oral Epithelial Cells?

    These cells should be stored in liquid nitrogen vapor phase at temperatures below -150°C to preserve their viability for future use.

  • What are the differences between Human Oral Epithelial Cells and other types of epithelial cells?

    Human Oral Epithelial Cells are specifically derived from the lining of the oral cavity, which gives them unique properties compared to other epithelial cells, such as those from the skin or respiratory tract. They are particularly well-suited for studies involving oral health, mucosal immunity, cancer, and tissue regeneration in the oral environment. Their gene expression profiles and responses to stimuli can differ significantly from other epithelial cell types, making them ideal for oral-specific research applications.

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