Human oligodendrocyte progenitor cells (OPCs) are a population of precursor cells found throughout the central nervous system (CNS). These cells possess the remarkable ability to differentiate into mature oligodendrocytes, which are specialized glial cells responsible for producing myelin, a lipid-rich membrane that provides insulation to neuronal axons. OPCs serve as a pool of migratory and proliferative adult progenitor cells, playing a crucial role in the generation and maintenance of myelinating cells in the CNS. Impaired differentiation of OPCs into mature oligodendrocytes is a significant factor contributing to the development of demyelinating diseases, highlighting the importance of understanding and harnessing the potential of these cells for therapeutic interventions.
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