The tissue of the central nervous system is made up of two classes of cells that may be broadly categorized as neurons and glia. Neurons are anatomic, functional, and trophic units of the brain. Despite great variability in size and shape, all neurons share common morphologic features, which are those of the key elements of a highly complex communication network. The neurons are the dynamically polarized cells that serve as the major signaling unit of the nervous system. The human brain is known to contain about 1 x 10^11 neurons, each being able to contact at least 10,000 other neurons. The hippocampal neurons play a special role in learning and memory and cultured hippocampal neurons are a useful model for studying neuronal phenomena such as differentiation, survival, process growth, and synapto-genesis.HHN from AcceGen Research Laboratories are isolated from hippocampal tissue of the brain. HHN are cryopreserved at primary cultures and delivered frozen. Each vial contains >1 x 10^6 cells in 1 ml volume. HHN are characterized by immunofluorescent method with antibodies to neurafilament, MAP2, and beta-tubulin III. HHN are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HHN are guaranteed to further culture in the conditions provided by AcceGen Research Laboratories.
