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Human Kidney Fibroblasts | ||||
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| Product Name | Human Kidney Fibroblasts | |||
| Price | Get Quote | |||
| Cat.No | ABC-TC5519 | Species | Human | |
| Size/Quantity | 1 vial | |||
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | Human kidney fibroblasts (HKF), or renal fibroblasts, are mesenchymal cells that display spindle-shaped morphology. They can be found in renal cortical interstitium and play an important role in maintaining extracellular matrix (ECM) homeostatic by controlling ECM production and degradation. Abnormal kidney fibroblast proliferation can lead to kidney ECM accumulation and often lead to renal fibrosis, which may develop into chronic kidney disease. Kidney interstitial fibroblast also plays a key role in endocrine control. They are the source of erythropoietin (EPO), a glycoprotein hormone that is central for proliferation and differentiation of erythroid progenitor cells. A well-functioned renal cortical fibroblast can protect human against anaemia. Why Choose Human Kidney Fibroblasts from AcceGen? All kidney fibroblasts have passed QC test and been confirmed negative for HIV-1, HIV-2, Hepatitis B and Hepatitis C as detected by serology or PCR. Cells are also tested negative for mycoplasma and other detectable microbial contaminations. | |||
| Disease | Normal | |||
| Source Organ | Kidney | |||
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
| Recommended Medium And Supplement | ABM-TM5519 Human Kidney Fibroblasts Medium Kit | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | For research use only | |||
| Key Features | -Backed by AcceGen advanced technology | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Fibroblast | |||
| Growth Mode | Adherent | |||
| Product Type | Renal Cells | |||
| Product Image |  | |||
Frequently Asked Questions
What are Human Kidney Fibroblasts (HKFs)?
Human Kidney Fibroblasts (HKFs) are specialized cells derived from the connective tissue of the human kidney. They play a crucial role in the structural support of the kidney and are involved in the production of extracellular matrix proteins.
How are Human Kidney Fibroblasts (HKF) typically cultured?
HKFs are cultured in fibroblast growth medium supplemented with specific growth factors. The optimal culture conditions include a temperature of 37°C, 5% CO2, and a humidified atmosphere to ensure cell viability and proliferation.
How do HKFs contribute to the study of renal fibrosis?
HKFs are instrumental in research on renal fibrosis as they are the primary cells responsible for the excessive production of extracellular matrix components in response to kidney injury. This makes them an ideal model to study the pathogenesis of fibrosis and test anti-fibrotic drugs.
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