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Primary Cells

Human Keratocytes

  • BSL

    1

  • 82
The keratocyte, or corneal fibroblast, is a highly specialized cell that is sandwiched between orthogonally arranged layers of collagen lamellae in the corneal stroma. They play a key role in maintaining the structure and transparency of the cornea as they are the source of stromal collagen and proglycans. They also play important roles in corneal […]
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Isolated from human corneal stroma, Human Keratocytes (HKs) are also known as corneal fibroblasts. Human Corneal Keratocytes (HCK) are sandwiched in the corneal stroma, between orthogonally arranged layers of collagen lamellae. HCK are highly specialized. Keratocytes are the source of stromal collagen and proglycans, therefore, they play an important role in transparency maintenance, wound healing, and synthesizing its components. Signaling molecules such as IL1 alpha and TNF-alpha secreted by the upper layers prompt keratocytes apoptosis after cornea injury or trauma. And neighboring keratocytes become active, proliferate and synthesizing matrix metalloproteinases to promote tissue remodeling when they are acted upon by those molecules.
Why Choose Human Keratocytes from AcceGen?
AcceGen cryopreserves Human Keratocytes for over 5 x 10^5 cells/mL at passage 1, for the best viability and plating efficiency after extensive testing and optimizations. AcceGen Human Keratocytes are guaranteed to further expand for 15 population doublings.

Product Code

HK

Species

Human

Cat.No

ABC-TC3663

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

keratinocyte

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Retina

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Ocular Cells

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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Application

  • For research use only.

  • Study the gene expression and therapeutic targets of the corneal inflammation.
  • Study the excessive apoptosis of keratocyte and its role in pathological process in the degenerative corneal disorders.

Inquiring Human Keratocytes

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High Viability
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Precision and Reliability
To support a consistent result
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Tags

  • Human (1729)
  • Keratocyte (1)
  • Normal (1578)
  • Ocular (18)
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