Human Keratinocytes, Adult

Keratinocytes are the major cells to form the epidermis, which is one of the main structural layers of human skin. Keratinocytes are located in the basal layer of the epidermis, and can transform into corneocytes of stratum corneum at the granular layer of epidermis. Keratinocytes play an important role as a barrier against biological, physical, and chemical agents. There are two fates of keratinocytes: differentiation and activation. In the normal epidermis, keratinocytes are distinguishably differentiated into four types: basal, spinous, granular and cornified. Apart from differentiation, keratinocytes can also be activated during wound healing or under pathologic conditions. Activated keratinocytes are migratory and hyperproliferative. To maintain undifferenciatied and proliferative keratinocytes, serum-free and low calcium growth medium(such as SFM) is used in the cultivation.

Why Choose Human Keratinocytes from AcceGen?

AcceGen provides high-quality human keratinocytes with the amount of at least 5×10⁵ cells in 1mL. Based on the strict test projects and quality control, we guarantee all human keratinocyte products are testing negative for bacteria, fungi, mycoplasma, HIV, HCV, HBV, and they can be further expanded for at least 15 population doublings in complete growth medium. The viability of human keratinocytes is more than 70% thawed from cryopreservation.