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Human Intestinal Epithelial Cells

  • BSL

    1

  • 435
cryopreserved InEpC are truly primary cells representing both villi (enterocytes, goblet, and enteroendocrine cells) and crypts structures. In combination with human intestinal myofibroblasts (InMyoFib).
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Home | Primary Cells | Human Primary Cells | Digestive System Primary Cells | Human Intestinal Epithelial Cells
Product Code

InEpC
Species

Human
Cat.No

ABC-TC3879
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Intestine
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Intestinal Cells
Key Features

-Backed by AcceGen advanced technology
-Ship cryopreserved cells in dry ice
-Quality-tested for accurate results

Description

Human Intestinal Epithelial Cell Features
Human Intestinal Epithelial Cells (IEC) are a layer of cells that line the luminal surface of intestinal epithelium. Stem cells located in crypts continuously produce new IECs at the base of the intestinal glands so that IECs could renew and migrate every 4-5 days.

Human Intestinal Epithelial Cells Function
Intestinal epithelial cells play an important part in the maintenance of the symbiotic relationship between gut microbiota and the host. IECs support the food digestion, nutrient absorption, protection of organism from bacteria and toxins and coordination of appropriate immune responses etc. IECs function as a barrier through constructing mucosal barriers, secreting immunological mediators like cytokines and chemokines, and delivering bacterial antigens.
The dysfunction of intestinal epithelial cells will cause diseases such as inflammatory bowel disease (IBD), celiac disease, and diarrhoeal infection.

Why Choose Human Intestinal Epithelial Cells from AcceGen?
AcceGen cryopreserves our Human Intestinal Epithelial Cells for about 8 x 10^5 cells/vial at passage 0, with a viability and plating efficiency ≥ 50% coverage at certain cell density after extensive testing and optimizations. Human Intestinal Epithelial Cells maintain their properties for about 5 days.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • For research use only

  • Human Intestinal Epithelial Cells Application
  • Establish an available epithelial cell culture system to investigate the exact pathogenesis of gastrointestinal diseases.
  • Intestinal epithelial cells could build infection models that help better understand the host-parasite interactions, extracellular matrix–cell interactions, microbiota interfaces, and population screens.

Frequently Asked Questions

  • What are Human Intestinal Epithelial Cells?

    Human Intestinal Epithelial Cells (IECs) are the cells that line the surface of the intestines. They form a barrier between the interior of the intestine and the rest of the body, playing a crucial role in nutrient absorption, immune function, and maintaining the integrity of the intestinal lining.

  • Where are Human Intestinal Epithelial Cells isolated from?

    Human intestinal epithelial cells are isolated from the entire intestine, including the small intestine and the large intestine

  • What functions do Human Intestinal Epithelial Cells perform in the gut?

    Human Intestinal Epithelial Cells are responsible for several key functions, including absorption of nutrients and water, secretion of digestive enzymes and mucus, maintenance of the intestinal barrier, and participation in immune responses by interacting with gut-associated lymphoid tissues.

  • How many times can Human Intestinal Epithelial Cells be passaged?

    Human Intestinal Epithelial Cells can typically be passaged 3-5 times. However, with each passage, the characteristics of the epithelial cells gradually change. Therefore, it is generally recommended to use these cells within three passages.

  • What are Human Intestinal Epithelial Cells used for in research?

    Human Intestinal Epithelial Cells are used in research to study intestinal physiology, pathophysiology, and diseases such as inflammatory bowel disease (IBD), colorectal cancer, and infections. They are also used in drug absorption and toxicity studies, as well as in the development of new therapeutic strategies.

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