Human Intestinal Epithelial Cell Features
Human Intestinal Epithelial Cells (IEC) are a layer of cells that line the luminal surface of intestinal epithelium. Stem cells located in crypts continuously produce new IECs at the base of the intestinal glands so that IECs could renew and migrate every 4-5 days.
Human Intestinal Epithelial Cells Function
Intestinal epithelial cells play an important part in the maintenance of the symbiotic relationship between gut microbiota and the host. IECs support the food digestion, nutrient absorption, protection of organism from bacteria and toxins and coordination of appropriate immune responses etc. IECs function as a barrier through constructing mucosal barriers, secreting immunological mediators like cytokines and chemokines, and delivering bacterial antigens.
The dysfunction of intestinal epithelial cells will cause diseases such as inflammatory bowel disease (IBD), celiac disease, and diarrhoeal infection.
Why Choose Human Intestinal Epithelial Cells from AcceGen?
AcceGen cryopreserves our Human Intestinal Epithelial Cells for about 8 x 10^5 cells/vial at passage 0, with a viability and plating efficiency ≥ 50% coverage at certain cell density after extensive testing and optimizations. Human Intestinal Epithelial Cells maintain their properties for about 5 days.
