Gingival Fibroblasts (GF) are the most abundant cell types found in gingival connective tissue. The key function of gingival fibroblast is to synthesis and maintain extracellular matric (ECM) and repair tissue upon oral damage. Human gingival fibroblasts also play a key role in sustaining inflammation response by interacting with pathogens and their component lipopolysaccharide (LPS) in periodontal disease. Due to its accessibility, superior wound closure rate, and low donor site morbidity compared to fibroblasts in other tissues, gingival fibroblast culture represents an ideal source for in vitro periodontal study and good substitute for mesenchymal stem cells (MSCs).
Why Choose Human Gingival Fibroblasts from AcceGen
AcceGen Human Gingival Fibroblasts are isolated from human gingiva tissue following standardized protocols. Cells are cryopreserved at passage 2 with each vial containing more than 5×10^5 cells in 1 ml volume. Human gingival fibroblasts are not detected with HIV-1, HBV, HCV and other pathogens. Cells are characterized with expression of fibronectin by immunofluorescence. Human gingival fibroblasts are quality tested for further expansion of 15 population doublings with stable activity and morphology in AcceGen culture media.
