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| Product Code | HFLS |
| Species | Human |
| Cat.No | ABC-TC3619 |
| Quality Control | All cell lots test negative for HIV-1, HBV, HCV, mycoplasma, yeast, fungi, and other pathogens. |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast-Like |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | synovium |
| Disease | Normal |
| Storage | Liquid Nitrogen |
| Product Type | Synoviocytes |
| Key Features | – Backed by AcceGen advanced technology – Cryopreserved for highest viability and plating efficiency – Quality-guaranteed for accurate results – Timely technical support for best experimental outcomes |
Human Fibroblast-Like Synoviocytes (HFLS) are primary fibroblast-like synoviocytes (FLS) isolated from normal human synovial membrane tissue. FLSs are type B synovial cells, and type A synovial cells are macrophage-like synovial cells. The function of FLS is to produce hyaluronan and other extracellular components in the synovial fluid to maintain the physiological functions of the synovial membrane. Synovial membrane plays an indispensable role in the mechanical movement of joints, and FLS plays an essential role in maintaining the stability of synovial structure and function. FLS shows several aggressive pathological changes and directly changes the synovial microenvironment, which is related to several joint diseases, such as synovial tumors and arthritis, especially rheumatoid arthritis (RA).
Why choose Adult HFLS of Normal Tissue from AcceGen?
AcceGen cryopreserves our HFLSs in the second passage for the best viability and plating efficiency. Adult primary HFLS of Normal Tissue provided by AcceGen can be cultured and propagated at least 5 population doublings.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
For research use only
Human Fibroblast-Like Synoviocytes (HFLS) isolated from healthy normal synovial membrane tissue are ideal control samples. And they can be used to establish in vitro models closer to the actual internal genetic, physiological and pathological status. HFLS is widely used in researching the physiological and pathological mechanism of the synovial membrane and joint-related diseases such as RA and synovial tumors.
