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Human Epidermal Keratinocytes, Adult (HEKa) are primary cells derived from adult skin and preserved through cryopreservation. Constituting the predominant cellular population in the epidermis, the outermost skin layer, they account for approximately 90% of all epidermal cells. Their pivotal role lies in the synthesis of keratin, the principal intermediate filament responsible for upholding the skin’s barrier function. Furthermore, these keratinocytes engage in interactions with epidermal melanocytes, facilitating the acquisition and sequestration of melanin as a defense mechanism against harmful UV radiation, thus fortifying the skin’s photoprotective capabilities.
Why choose Human Epidermal Keratinocytes, Adult from AcceGen?
AcceGen’s Human Epidermal Keratinocytes, Adult exhibit exceptional features, including high viability and assurance of 16 population doublings for cryopreserved cells. These cells are rigorously screened, testing negative for mycoplasma, bacteria, yeast, and fungi. Each purchase includes a Certificate of Analysis, ensuring product quality and reliability.
Species | Human |
Cat.No | ABC-TC3604 |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Others |
Size/Quantity | 1 vial |
Cell Type | Keratinocyte |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Epidermal |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Keratinocyte |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
Human Epidermal Keratinocytes, Adult (HEK) are versatile tools in various research areas. They play a pivotal role in toxicology, wound repair, skin cancer, UV radiation response, psoriasis, eczema, viral infection, gene delivery systems, and cosmetics research/testing. These cells offer an excellent model system for studying epithelial function and diseases, particularly in the context of skin biology, toxicology, and HPV infection. When cultured on inserts with a liquid/air interface, HEK can differentiate into a stratified squamous epithelium, providing a more physiologically relevant 3D tissue model for in vitro studies.