Dopaminergic neurons are a type of neurons within the central nervous system (CNS).Although they make up a tiny proportion of the total neuronal population in the CNS,they are responsible for the synthesis and release of dopamine (DA), a keyneurotransmitter. Dopaminergic neurons are primarily located in discrete areas of the brain, particularly the substantia nigra (SN) and ventral tegmental area, and are involved in fundamental physiological processes including motor control, motivation,reward mechanisms, and mood regulation. Progressive degeneration of dopaminergic neurons reduces DA levels in the SN and striatum and triggers the onset of clinical symptoms of Parkinson’s disease (PD), a common neurodegenerative movement disorder, such as tremor, postural instability, bradykinesia, and muscle rigidity.
Why choose Human Dopaminergic Neurons (iPSC-derived, Normal) from AcceGen?
AcceGen’s Human iPSC-derived Dopaminergic Neurons were cryopreserved and delivered frozen. The cells were maintained at 37℃ with 5% CO2. The number of cells was 1.0 million cells/vial. All cells were negative for mycoplasma, bacteria,yeast and fungi.
