Human Chondrocytes (Osteoarthritis)

Human Chondrocytes (Osteoarthritis), also referred to as HC-OA, are obtained from the articular cartilage of individuals afflicted with osteoarthritis (OA). Osteoarthritis is an inflammatory ailment characterized by the heightened degradation of cartilage tissue within the joints, attributed to the excessive production of enzymes that break down the extracellular matrix. Despite the initial proliferation and activation of chondrocytes, they lack the ability to effectively restore the deteriorating cartilage. Instead, chondrocytes undergo a process of terminal differentiation and eventually undergo programmed cell death, resulting in the mineralization of cartilage that resembles bone formation during developmental stages.

Why choose Human Chondrocytes (Osteoarthritis) from AcceGen?

AcceGen is the ideal choice for Human Chondrocytes (Osteoarthritis) due to our provision of high-quality cells. HC-OA cells are isolated from osteoarthritic donors, cryopreserved at P1, and each vial contains >0.5 million cells. These HC-OA cells are positive for aggrecan after differentiation and are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They are expandable for 10 population doublings under AcceGen’s recommended conditions.