Human CD16a (158F) (Luc) Jurkat Reporter Cell
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The Human CD16a (158F) (Luc) Jurkat Reporter Cell was engineered to not only express the NFAT response element driving luciferase expressing systems, but also express full length human CD16a (158F) receptor (Gene ID: 2214) exhibiting a lower affinity for IgG1 and IgG3 isotypes compared to CD16a-158V, which can use to evaluate ADCC activity of antibodies in the presence of corresponding target cells. When co-cultured with a target cell and relevant antibody, the antibody simultaneously binds the target cell antigen and CD16a (158F) receptor on the surface of Human CD16a (Luc) (158F) Jurkat Reporter Cell, resulting in receptor clustering, intracellular signaling and NFAT-mediated luminescence.
Species | Human |
Cat.No | ABC-RC080F |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 1 vial |
Cell Type | T Lymphoblast |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Blood |
Disease | Acute T Cell Leukemia |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Reporter Stable Cell Lines |
Host Cell | Jurkat |
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For research use only