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Human Brain Microvascular Endothelial Cells | ||||
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| Product Name | Human Brain Microvascular Endothelial Cells | |||
| Price | Get Quote | |||
| Cat.No | ABC-TC3524 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | Human Brain Microvascular Endothelial Cells (HBMECs), derived from human brain, are one type of brain endothelial cells and the central element of the microvasculature which forms the blood-brain barrier (BBB). HBMECs limit the passage of soluble and cellular substances from the blood into the brain and shield the brain against toxins and immune cells. Brain microvascular endothelial cells can express cell adhesion molecules on their surface to regulate the extravasation of leukocytes into the brain. However, extracellular host-pathogen interactions can trigger calcium signaling in the endothelial cells, causing pathogen penetration through the BBB. GFP-Human Brain Microvascular Endothelial Cells (GFP-HBMECs) and Immortalized Human Brain Microvascular Endothelial Cells (IM-HBMECs) are also available in AcceGen. | |||
| Disease | Normal | |||
| Source Organ | Brain | |||
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
| Recommended Medium And Supplement | ABM-TM3524 Human Brain Microvascular Endothelial Cells Medium Kit | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | For research use only. | |||
| Key Features | -Backed by AcceGen advanced technology | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Endothelial | |||
| Growth Mode | Adherent | |||
| Product Type | Nervous Cells | |||
| Product Image |  | |||
Frequently Asked Questions
What are the primary research applications of Human Brain Microvascular Endothelial Cells?
These cells are commonly used in studies of the blood-brain barrier, neuroinflammation, and drug transport across the brain endothelium.
What are the recommended culture conditions for Human Brain Microvascular Endothelial Cells?
These cells should be cultured in a specialized endothelial growth medium, under standard cell culture conditions (37°C, 5% CO2).
What functional assays can be used with Human Brain Microvascular Endothelial Cells?
Functional assays for Human Brain Microvascular Endothelial Cells include permeability assays, transendothelial electrical resistance (TEER) measurements, and migration assays. These assays are used to study the barrier properties and dynamics of these cells.
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