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| Species | Human |
| Cat.No | ABC-TC4367 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bladder |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Bladder Cells |
Human bladder epithelial cells are the primary cells isolated from the human urinary bladder. Human bladder epithelium is specialized lining epithelium consisting of 3-7 layers of cells, which are classified into three types: basal cells (cuboidal cells), intermediate cells (polygonal cells), and umbrella cells at the apical layer. In some points, human bladder epithelium cells are thought to transform from basal cells to intermediate cells, and then to umbrella cells; however, some studies also indicated that both basal cells and intermediate cells are the precursor cells that can differentiate into umbrella cells. Primary human bladder epithelial cells grow slowly: 10-14 days to fully recover from cryopreservation; 7-10 days to reach 70%-90% confluence in the subculture. 
The biomarkers of human bladder epithelium cells includes: CK5+, CK7+, CK8+, CK18+, P63+, E-cadherin+, Zona occludens 1 (ZO-1)+, and α-smooth muscle Actin–.
Why choose Human Bladder Epithelial Cells from AcceGen?
Human bladder epithelial cells from AccGen were prepared with our rigorous standards and by professional operators to ensure high cell viability of more than 70% after thawing. All the procedures are precisely controlled in a sterile condition that all cells are negative for bacterial, fungal, and mycoplasma contamination.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
Human bladder epithelial cells provide a valuable in vitro model for studying and understanding the complex responses of the urinary bladder to various physiological and pathological conditions. By subjecting these cells to stretching forces, osmotic and hydrostatic pressures, exposure to toxins, and microbial invasion, researchers can gain insights into the molecular and cellular mechanisms underlying bladder function and dysfunction. Human bladder epithelial cells offers a unique opportunity to investigate the formation, progression, and resolution of diseases such as urinary tract infections and bladder cancer.
