Mouse iPS cell line (induced pluripotent stem cell line) was derived from mouse embryonic fibroblasts (MEFs) by retroviral expression of Oct3/4, Sox2, Klf4 and c-Myc genes. The cells were derived using morphological selection criteria and without the use of fluorescent marker or drug selection. When cultured under standard mouse ES cell culture conditions, the morphology […]
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Mouse induced pluripotent stem (iPS) cells were generated from mouse embryonic fibroblasts (MEFs) through the introduction of Oct3/4, Sox2, Klf4, and c-Myc genes using retroviral expression. Selection of the cells was based on their morphological characteristics, without the need for fluorescent markers or drug selection. These mouse iPS cells exhibit an indistinguishable morphology from mouse embryonic stem (ES) cells when cultured under standard ES cell conditions. They express key pluripotency markers such as SSEA-1 and Nanog, along with robust endogenous alkaline phosphatase activity. To support their growth, mouse iPS cells are cultured on a feeder layer of MEFs, necessitating pretreatment of the culture plate with Gelatin.
Why choose HighQC™Mouse iPS Cell Line from AcceGen?
The Mouse iPS cell line from AcceGen is an excellent choice for several reasons. Firstly, we offer low passage cells with long-term viability, ensuring the maintenance of cell quality and functionality over extended periods. Secondly, these cells are readily available off the shelf, allowing for simple thawing and plating onto a serum-free, feeder-free culture system. This convenience saves time and effort in the laboratory. Lastly, the Mouse iPS cell line from AcceGen guarantees homogeneity as it originates from a single iPSC clone. This ensures consistency and uniformity in experimental results, making it an ideal choice for research and scientific studies.
Species
Mouse
Cat.No
ABC-SC2115
Product Category
Stem Cells
Size/Quantity
1 vial
Cell Type
Induced Pluripotent Stem Cell
Shipping Info
Dry Ice
Growth Conditions
37 ℃, 5% CO2
Disease
Normal
Storage
Liquid Nitrogen
Product Type
Animal induced Pluripotent Stem Cells
Citation
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Application
FOR RESEARCH USE ONLY
The mouse iPS cell line has a wide range of applications, particularly in research and preclinical studies. These cells serve as a valuable model for investigating genetic and epigenetic changes in the development of regenerative medicine. By studying mouse iPS cells, researchers can gain insights into the underlying mechanisms of disease and develop effective therapeutic strategies. Additionally, these cells are instrumental in evaluating and optimizing the therapeutic efficacy of innovative vaccines, such as iPSC-derived dendritic cells, in the treatment of various cancers. Overall, the mouse iPS cell line offers a versatile platform for advancing scientific knowledge and developing novel approaches for disease treatment.
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Why choose HighQC™ Mouse iPS Cell Line from AcceGen?
