Mesenchymal stem cells (MSC) are a well-characterized population of adult stem cells. MSC have the potential to develop into mature cells that produce fat, cartilage, bone, tendons, and muscle. This property, in combination with MSC’s developmental plasticity, has generated tremendous interest in the potential use of MSC to replace damaged tissues. Fetal lung has been identified as a rich source of MSCs and has been reported that MSCs can differentiate into neural cells in addition to their mesenchymal differentiation potential; enhance the engraftment of human umbilical cord blood-derived CD34 hematopoietic cells in nonobese diabetic-severe combined immunodeficiency mice. Flow cytometric analysis showed that fetal lung MSCs expressed CD13, CD29, CD44, CD90, CD105, CD166, and HLA-ABC.HPMSC from AcceGen Research Laboratories are isolated from lung tissue. HPMSC are cryopreserved at passage one culture and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HPMSC are characterized by immunofluorescent method with antibodies to CD73, CD90 and CD105. HPMSC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HPMSC are guaranteed to further culture at the conditions provided by AcceGen Research Laboratories.
