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HighQC™ Human Mobilized Peripheral Blood CD34+ Stem/Progenitor Cells; G-CSF And CXCR4 Antagonists

  • BSL
  • 78
CD34 is most commonly associated with expression on hematopoietic progenitor cells found in bone marrow and cord blood. While compromising only 1.5% of bone marrow mononuclear cell population, CD34 stem cells are multipotent and responsible for all lymphohematopoietic lineages. These cells are now commonly used clinically as they have been shown to provide long-term durable […]
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Home | Stem Cells | Adult Stem Cells | HighQC™ Human Mobilized Peripheral Blood CD34+ Stem/Progenitor Cells; G-CSF And CXCR4 Antagonists
Species

Human
Cat.No

ABC-SC0091T
Product Category Stem Cells
Size/Quantity

1 vial
Cell Type

Stem Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Mobilized Peripheral Blood
Storage

Liquid Nitrogen
Product Type

Human Adult Stem Cells

Description

CD34 is most commonly associated with expression on hematopoietic progenitor cells found in bone marrow and cord blood. While compromising only 1.5% of bone marrow mononuclear cell population, CD34 stem cells are multipotent and responsible for all lymphohematopoietic lineages. These cells are now commonly used clinically as they have been shown to provide long-term durable donor-derived host lymphohematopoietic reconstitution.

Donors are injected with a combination of CXCR4 antagonists and G-CSF, which stimulates the bone marrow to produce a large number of hematopoietic and progenitor stem cells and mobilizes them into the peripheral blood stream.

CD34+ cells are isolated using positive immunomagnetic cell separation procedures from a mobilized leukapheresis collection.

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