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| Species | Human |
| Cat.No | ABC-SC0123T |
| Product Category | Stem Cells |
| Size/Quantity | 1 vial |
| Cell Type | Induced Pluripotent Stem Cell |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Biosafety Level | 2 |
| Storage | Liquid Nitrogen |
| Product Type | Human iPSCs |
CHD8 has a role in chromatin dynamic, transcription and cell survival in which it interacts with p53 to regulate cell cycle genes. It has been associated with developmental disorders like ASD (autism spectrum disorders). CHD8+/− iPSC were derived from skin fibroblasts obtained from a typically developing male control who had a normal karyotype, in which a CHD8 allele was knocked out using CRISPR/Cas9 gene editing. The two lines can be utilized by researchers interested in brain development, neurodevelopmental disorders, and cancer.
When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
For research use only
