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Tumor Cell Lines

Hep 3B

  • BSL
  • 249
Derived from an 8 year old male. Cells contain integrated Hepatitis B virus genome. However there is currently no evidence that this cell line produces infectious Hepatitis B virus. The cells should be handled under laboratory containment level 2. Ethnicity: Black.
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Hep 3B is a human hepatoma cell line originally derived from liver tissue obtained from an 8-year-old Black patient with liver cancer.Hep 3B These cells harbor an integrated hepatitis B virus genome and display an epithelial morphology. Notably, Hep3B cells possess tumorigenic properties in nude mice. Chromosomally, they maintain an average of 60 chromosomes per cell, with a predominant subtetraploid mode of 82. In terms of gene expression, this cell line exhibits the production of various proteins including alpha-fetoprotein (AFP), hepatitis B surface antigen (HBsAg), albumin, alpha-2-macroglobulin, alpha-1-antitrypsin, transferrin, alpha-1-antichymotrypsin, haptoglobin, ceruloplasmin, plasminogen complement (C3, C4), C3 activator, fibrinogen, alpha-1 acid glycoprotein, alpha-2-HS-glycoprotein, beta-lipoprotein, and retinol-binding protein.

 

Why choose Hep 3B from AcceGen?

Hep 3B cells from AcceGen offer exceptional viability and quality, cultivated under expert care in optimal conditions, ensuring sterility by being free of bacteria, fungi, and mycoplasma. Their identity is confirmed through STR analysis, and they are detected to express HBV, making them a reliable choice for various research applications.

Product Code

Hep 3B2_1-7; HEP3B217; Hep 3B2; HEP-3B2; HEP3B2; Hep-3B; HEP-3B; Hep 3B; Hep3B; HEP3B

Species

Human

Cat.No

ABC-TC5585

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Liver

Disease

Hepatocellular Cancer

Storage

Liquid Nitrogen

Product Type

Human Liver Cancer Cell Lines

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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Application

  • FOR RESEARCH USE ONLY

  • The Hep 3B cell line serves as a vital tool in biomedical research, particularly in elucidating the intricate relationship between HBV infection and the development of hepatocellular carcinoma. Additionally, these cells find widespread utility in drug metabolism and hepatotoxicity studies, offering insights into the effects of various compounds on the liver. Furthermore, Hep3B cells are valuable for investigating plasma protein biosynthesis and studying the interplay between the hepatitis B virus genome and tumorigenicity, making them indispensable for a range of experimental models and scientific inquiries.

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Tags

  • Epithelial (292)
  • Human (1729)
  • Liver (143)
  • Liver Cancer (32)
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