For research use only
| Cat No. | ABC-TC0354 |
| Product Type | Human Uterine Cancer Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cervix |
| Disease | Cervix Cancer |
| Product Code | HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri |
HeLa cells are HPV18-positive cervical cancer cells applied in tumorigenesis modeling, viral gene expression, and epithelial transformation studies.
HeLa is a human cervical carcinoma cell line that was originally isolated from the cervix tissue of a 31-year-old Black female patient with cervical adenocarcinoma; it’s the first established human immortal cell line. HeLa exhibits epithelial-like morphology and adherent culture properties. The stemline karyotype of HeLa is around 76–80, with a large proportion of chromosome mutations. They are characterized by rapid proliferation and genomic instability due to HPV-18 integration and subsequent p53 inactivation (due to E6-mediated degradation). HeLa cells demonstrate robust keratin expression by immunostaining, confirming their epithelial lineage. Key markers include cytokeratins (epithelial origin) and high telomerase activity. HeLa cells are highly adaptable, thriving in diverse culture conditions, and are extensively used in cancer research, virology (e.g., HPV, HIV), and drug screening. Their robust nature and ease of transfection make them a cornerstone in molecular biology, vaccine development, and cytotoxicity studies.
| Product Code | HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri |
| Species | Human |
| Cat.No | ABC-TC0354 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cervix |
| Disease | Cervix Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Uterine Cancer Cell Lines |
HeLa cells are indispensable for cancer biology studies, including apoptosis, metastasis, and drug resistance mechanisms. They serve as a model for HPV pathogenesis, viral replication (e.g., SARS-CoV-2), and vaccine production. Moreover, HeLa cells serve as transfection hosts for gene function and regulation studies, recombinant protein production, and gene therapy investigations. Other applications include gene expression studies (transfection/transduction), protein production, and toxicity testing. Their use in high-throughput screening (e.g., siRNA libraries) and radiation biology (due to radiosensitivity) further underscores their versatility.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Kim MJ, Lee HJ, Choi MY, et al. UHRF1 induces methylation of the TXNIP promoter and Down-Regulates gene expression in cervical cancer. Molecules and Cells. 2021;44(3):146-159. doi:10.14348/molcells.2021.0001
HeLa cells are an immortalized human cervical cancer cell line derived from Henrietta Lacks in 1951.
HeLa cells are not stem cells; they are cancer cells derived from cervical carcinoma. Their immortalized nature allows indefinite propagation in culture.
HeLa cells were the first human cells successfully cultured long-term. Their robustness and rapid growth have made them invaluable for studying cancer biology, virology, genetics, drug development, and cell physiology.
HeLa cells are epithelial-like, adherent cells that grow in clusters in vitro. They have a characteristic elongated or polygonal morphology under standard culture conditions.
