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Tumor Cell Lines

H357

  • BSL
  • 73
Established from a squamous cell carcinoma (SCC) of the tongue (20mm) of a 74 year-old male patient. STNMP stage I, well differentiated, node negative tumour. Mutant p53, codon 110 exon 4, G to A; the previously reported mutant Ha-ras status of this cell line: codon: 13, G to A, codon 61, A-G is under investigation. […]
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Established from a squamous cell carcinoma (SCC) of the tongue (20mm) of a 74 year-old male patient. STNMP stage I, well differentiated, node negative tumour. Mutant p53, codon 110 exon 4, G to A; the previously reported mutant Ha-ras status of this cell line: codon: 13, G to A, codon 61, A-G is under investigation. This cell line is highly responsive to TGF (Transforming growth factor )-β and undergoes epithelial to mesenchymal transition. It expresses high levels of TGF-β1. Fahey et al (1996). Tumourigenic in athymic nude mice on subcutaneous injection and non-tumorigenic on orthotopic injection. Haplotype information: A*02,A*31; B*40,B*44; Cw*03,Cw*05

Species

Human

Cat.No

ABC-TC5555

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Shipping Info

Dry ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Tongue

Disease

Oral Squamous Cell Cancer

Storage

Liquid Nitrogen

Product Type

Human Tongue Cancer Cell Lines

Citation

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Application

  • For research use only

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High Viability
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Tags

  • Human (1729)
  • Tongue (8)
  • Tongue Cancer (8)
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