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FADD Knockout Cell Lysate

  • BSL
  • 104
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of […]
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Home | Transfected Stable Cell Lines | Knockout Cell Lysate | FADD Knockout Cell Lysate
Species

Human
Cat.No

ABC-KC0649
Product Category Transfected Stable Cell Lines
Size/Quantity

100ug
Shipping Info

Ice Pack
Growth Conditions

37 ℃, 5% CO2
Storage

Store FADD KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.
Product Type

CRISPR Knockout Cell Lysate
Host Cell

HeLa

Description

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

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