Embryonic Mouse Hypothalamus Cell Line
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Embryonic Mouse Hypothalamus Cell Line is based on a proprietary platform technology which has enabled the creation of a series of Immortalised hypothalamic neurons; Immortalised from mouse embryonic day 15, 17, 18 hypothalamic primary cultures by retroviral transfer of SV40 T-Ag. These cell lines have been found to express an ever expanding array of neuropeptides, enzymatic markers and biologically active receptors.
As such, these cell lines enable accurate in-vitro assays for use in the discovery, development and validation of new therapeutics targeted to central-nervous system diseases and disorders, including obesity, stress, and metabolic disorders, amongst others.
Species | Mouse |
Cat.No | ABI-TC226 |
Product Category | Immortalized Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Hypothalamus Cell |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Brain |
Disease | Normal |
Storage | Liquid Nitrogen |
Product Type | Immortalized Cell Line |
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For research use only
An Embryonic Mouse Hypothalamus Cell Line is a culture of cells derived from the hypothalamic region of a mouse embryo. These cells are often immortalized to proliferate indefinitely, providing a stable model for studying the development and function of the hypothalamus, a critical brain region involved in regulating various physiological processes.
This cell line is used to investigate the molecular and cellular mechanisms underlying hypothalamic functions, such as hormone release, appetite regulation, and circadian rhythms. Researchers utilize these cells to study neurodevelopment, neuroendocrine interactions, and to model diseases related to hypothalamic dysfunction, such as obesity and metabolic disorders.
Consistency: Provides a consistent and reproducible model for hypothalamic research.
Prolonged Culture: Can be maintained and propagated over long periods, facilitating extensive studies.
Hypothalamic Characteristics: Retains key properties of hypothalamic neurons, enabling relevant physiological studies.