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The cells are resistant to 0.1 MM cortisol and sensitive to 20 mcg/ml PHA.
A subline (EL4.IL-2) produces high levels of interleukin-2 (IL-2, interleukin 2) is available.
Tested and found negative for ectromelia virus (mousepox).
| Product Code | EL-4; EL 4; E.L.4 |
| Species | Mouse |
| Cat.No | ABC-TC0242 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphoblast |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Blood |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Lymphocytes Cell Lines |
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For research use only
EL4 cells are NK-T cell tumors that may have a genetic mechanism that allows them to express a limited group of molecules involved in recognition and signaling. They are small, rounded, and can be oval or multiform, and they often grow singly in suspension. Some cells may have small hairs or fringes.
EL4 cells are resistant to 0.1 mM cortisol and sensitive to 20 μg/mL PHA. The cells have been reported to produce low levels of type G (Gross) virus antigen H-2b, IL-4 and Thy-1.2 antigen. They can also continuously produce exosomes that carry TRAIL protein, which can induce apoptosis and necrosis in 4T1 cells.
The doubling time of EL4 cells is approximately 12-20 hours, though this can vary depending on culture conditions.
