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DROSHA Knockout Cell Lysate

  • BSL
  • 51
This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm […]
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Home | Transfected Stable Cell Lines | Knockout Cell Lysate | DROSHA Knockout Cell Lysate
Species

Human
Cat.No

ABC-KC0547
Product Category Transfected Stable Cell Lines
Size/Quantity

100ug
Shipping Info

Ice Pack
Growth Conditions

37 ℃, 5% CO2
Storage

Store DROSHA KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.
Product Type

CRISPR Knockout Cell Lysate
Host Cell

HEK293T

Description

This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq, Sep 2016]

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

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