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Diseased Human Lung Fibroblasts, Idiopathic Pulmonary Fibrosis | ||||
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Product Name | Diseased Human Lung Fibroblasts, Idiopathic Pulmonary Fibrosis | |||
Price | Get Quote | |||
Product Code | DHLF-IPF | |||
Cat.No | ABC-TC5520 | Species | Human | |
Size/Quantity | 1 vial | |||
Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
Description | Lung fibroblasts are considered as the key effector cells in Idiopathic Pulmonary Fibrosis (IPF), an interstitial lung disease that commonly seen in elderly with unclear etiology. Characterized by excessive fibroproliferation and extracellular matrix accumulation, IPF is associated with progressive decline in lung function, poor diagnosis, and limited treatment option. Studies have suggested that transforming growth factor (TGF)-β induced alveolar epithelial cells (AEC) can undergo epithelial-mesenchymal transition (EMT) and serve as a source of fibroblast or myofibroblast in fibrosis. Aging is also a main contributor to IPF where senescence fibroblasts show abnormal metabolism and senescence-associated secretory phenotypes. | |||
Disease | Idiopathic Pulmonary Fibrosis | |||
Source Organ | Lung | |||
Recommended Medium And Supplement | ABM-TM5520 Diseased Human Lung Fibroblasts, Idiopathic Pulmonary Fibrosis Medium Kit | |||
Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
Application | For research use only | |||
Key Features | -Backed by AcceGen advanced technology | |||
Growth Conditions | 37 ℃, 5% CO2 | |||
Cell Type | Fibroblast | |||
Growth Mode | Adherent | |||
Product Type | Pulmonary Cells | |||
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