MENU

Home > Products > Tumor Cell Lines > Animal Tumor Cell Lines >

CT26-OVA

28

Product Name

CT26-OVA

Price Get Quote
Cat.No

ABC-TC002F

Species

Mouse

Cell Type

Fibroblast

Growth Mode

Adherent

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The CT26-OVA cell line is a variant of the CT26 murine colon carcinoma cell line that has been engineered to stably and highly express ovalbumin (OVA), a well-known immunogenic antigen protein.

In studies, the expression of OVA in CT26-OVA cells has been shown to increase their recognition by OVA-specific cytotoxic T-lymphocytes (CTLs). The CTLs recognize OVA fragments presented on MHC class I molecules, leading to targeted killing of the tumor cells. Additionally, research has demonstrated that CT26-OVA tumors exhibit a higher sensitivity to immune checkpoint inhibitors, such as anti-PD-1 therapy, compared to their parental CT26 counterparts.

Why choose CT26-OVA from AcceGen?
Choose CT26-OVA from AcceGen for its guaranteed mycoplasma-free status, ensuring contamination-free research. We offer quick delivery and ship on dry ice to maintain cell viability. Additionally, the cell line is STR-identified for authenticity, providing reliable, high-quality cells for your immuno-oncology studies.

Disease

Carcinoma

Source Organ

Colon

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement

RPMI 1640 + 10% FBS

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY
The CT26-OVA cell line is a valuable tool in immuno-oncology research, offering a robust model for studying immune responses and evaluating cancer therapeutics. Engineered to stably express the highly immunogenic ovalbumin (OVA) antigen, CT26-OVA cells enhance tumor-immune interactions, making them ideal for screening immunotherapies. These cells can establish tumors in vivo, enabling efficacy studies in animal models, particularly for immune checkpoint inhibitors like anti-PD-1. Researchers can use CT26-OVA to explore antigen presentation, cytotoxic T-lymphocyte (CTL) recognition, and tumor cell death, providing insights into mechanisms of immune evasion and the development of novel cancer treatments. This cell line serves as a powerful platform for advancing the field of cancer immunotherapy.

Growth Conditions

37 ℃, 5% CO2

Product Type

Mouse Colon Cancer Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial

Related Products

CMT-93

CMT-93

CMT93/69

CMT93/69

Colon-26

Colon-26

  • ONLINE INQUIRY
  • PRODUCT REVIEWS
We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time?

Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
Privacy Policy: AcceGen will never sell, rent, or share your personal information with any third parties without your express permission.
Reviews of CT26-OVA
AcceGen is always trying to do right by our customers and working hard to build a higher quality product.

Your email address will not be published.

AcceGen Scroll Top Button