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Tumor Cell Lines

CT26-OVA

  • BSL

    1

  • 56
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The CT26-OVA cell line is a variant of the CT26 murine colon carcinoma cell line that has been engineered to stably and highly express ovalbumin (OVA), a well-known immunogenic antigen protein.

In studies, the expression of OVA in CT26-OVA cells has been shown to increase their recognition by OVA-specific cytotoxic T-lymphocytes (CTLs). The CTLs recognize OVA fragments presented on MHC class I molecules, leading to targeted killing of the tumor cells. Additionally, research has demonstrated that CT26-OVA tumors exhibit a higher sensitivity to immune checkpoint inhibitors, such as anti-PD-1 therapy, compared to their parental CT26 counterparts.

Why choose CT26-OVA from AcceGen?
Choose CT26-OVA from AcceGen for its guaranteed mycoplasma-free status, ensuring contamination-free research. We offer quick delivery and ship on dry ice to maintain cell viability. Additionally, the cell line is STR-identified for authenticity, providing reliable, high-quality cells for your immuno-oncology studies.

Species

Mouse

Cat.No

ABC-TC002F

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Fibroblast

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Colon

Disease

Carcinoma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Colon Cancer Cell Lines

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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Application

  • FOR RESEARCH USE ONLY

  • The CT26-OVA cell line is a valuable tool in immuno-oncology research, offering a robust model for studying immune responses and evaluating cancer therapeutics. Engineered to stably express the highly immunogenic ovalbumin (OVA) antigen, CT26-OVA cells enhance tumor-immune interactions, making them ideal for screening immunotherapies. These cells can establish tumors in vivo, enabling efficacy studies in animal models, particularly for immune checkpoint inhibitors like anti-PD-1. Researchers can use CT26-OVA to explore antigen presentation, cytotoxic T-lymphocyte (CTL) recognition, and tumor cell death, providing insights into mechanisms of immune evasion and the development of novel cancer treatments. This cell line serves as a powerful platform for advancing the field of cancer immunotherapy.

Inquiring CT26-OVA

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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