COR-L24
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The COR-L24 cell line, originating from a lymph node biopsy of an untreated 71-year-old male diagnosed with small cell lung carcinoma (SCLC), serves as a valuable model in biomedical research. Derived from a xenograft forming culture, this cell line manifests as floating aggregates of densely packed cells with irregular shapes, representing the characteristic features of SCLC.
The COR-L24 cell line, established and characterized in 1985, COR-L24 cells maintain classic neuroendocrine properties synonymous with SCLC. Notably, the patient’s bone marrow, while hypercellular and indicative of normal hematopoietic cells, exhibited no evidence of neoplasm.
The well-documented history and neuroendocrine characteristics of COR-L24, coupled with its establishment from an untreated SCLC patient, position it as a representative and valuable tool for studying the pathobiology, therapeutic responses, and molecular aspects of small cell lung carcinoma.
Why choose ABC-TC0180 COR-L24 from AcceGen?
Elevate your studies with confidence, knowing that each AcceGen’s COR-L24 cell line undergoes rigorous quality control (QC) tests, ensuring the utmost reliability in your experiments.
Key Quality Control Measures:
Sterility Assurance:
COR-L24 cells are subjected to thorough testing to confirm negative results for bacterial, fungal, and mycoplasma contamination. Utilizing advanced PCR techniques, we ensure a sterile and uncontaminated cell culture environment. Additionally, the cells are verified to be free from human pathogens.
Identity Verification with STR Analysis:
Upholding the highest standards of authenticity, we conduct Short Tandem Repeat (STR) analysis using 16 probes, encompassing 15 STR loci plus Amelogenin. This rigorous identity check ensures the unequivocal authenticity of the COR-L24 cell line.
Morphology and Marker Expression Analysis:
COR-L24 cells exhibit growth characteristics meticulously assessed based on morphology and immunocytochemistry of multiple undifferentiation markers. This comprehensive evaluation ensures that COR-L24 maintains its intended properties for your research needs.
| Product Code | COR L24; Cor L24; CORL24 |
| Species | Human |
| Cat.No | ABC-TC0180 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lymph Node |
| Disease | Lung Small Cell Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lung Cancer Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
AcceGen’s COR-L24 cell line holds significant applications in various areas of scientific research. Here are some key applications of the COR-L24 cell line in science research:
Small Cell Lung Carcinoma (SCLC) Studies:
COR-L24 cells serve as a valuable model for studying the pathobiology, molecular characteristics, and therapeutic responses associated with small cell lung carcinoma, contributing to advancements in lung cancer research.
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Therapeutic Drug Screening
The COR-L24 cell line is often utilized in drug screening assays to evaluate the efficacy of potential therapeutic agents for the treatment of small cell lung carcinoma. This aids in the identification and development of novel anti-cancer drugs.
Immunocytochemistry and Marker Expression
COR-L24 cells can be employed in immunocytochemistry studies to analyze the expression of specific markers associated with small cell lung carcinoma and neuroendocrine differentiation. This aids in the characterization of cellular identity.
