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CCD-18Co

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Product Name

CCD-18Co

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Product Code

CCD18Co; CCD18

Cat.No

ABC-TC0120

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

CCD-18Co is a non-malignant human fibroblast cell line that originates from normal colon tissue. Notably, the activation of CCD-18Co cells can be effectively suppressed by the compound Calycosin (CA). Furthermore, it has been observed that the media conditioned by these human colonic CCD-18Co fibroblasts has the ability to enhance the proliferation of human colon cancer HT-29 cells. Interestingly, pretreatment with Cathelicidin demonstrates the capacity to inhibit colon cancer cell proliferation induced by the media conditioned by CCD-18Co fibroblasts. In terms of subculturing, it is recommended to split confluent CCD-18Co cells with a ratio of 1:2 to 1:3 every 2 to 3 days.

 

Why choose CCD-18Co from AcceGen?

CCD-18Co cells are characterized by their exceptional viability and quality, cultivated under optimal conditions and preserved through advanced cryopreservation techniques. These cells maintain sterility and are confirmed to be mycoplasma-free, ensuring the integrity of experiments. Their identity is verified through STR analysis, providing reliable and consistent research tools.

Disease

Normal

Source Organ

Colon

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

CCD-18Co, a non-transformed cell line, finds versatile applications in cancer research. It serves as a crucial normal control in cancer studies and plays a pivotal role in establishing the fibroblastic component within co-culture models that explore epithelial-stromal interactions in colon cancer. Additionally, CCD-18Co cells are instrumental in unraveling the mechanisms underlying pathological fibrosis resulting from colon inflammation, making them invaluable tools for studying both cancer and inflammatory-related conditions in the colon.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Fibroblast

Growth Mode

Adherent

Product Type

Human Colon Cancer Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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