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Primary Cells

C57BL/6 Mouse Type II Alveolar Epithelial Cells

  • BSL

    1

  • 151
C57BL/6 Mouse Type II Alveolar Epithelial Cells are cryopreserved carefully using AcceGen cryopreservation protocol that ensures high viability (typically > 70%) after thawing. Cells should be stored at < -120°C once they are received, such as within a liquid nitrogen tank.
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  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Species

C57BL/6 Mouse

Cat.No

ABC-H0084X

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Alveolar

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Primary Cells

Description

C57BL/6 Mouse Type II Alveolar Epithelial Cells, derived from C57BL/6 mouse lungs, comprise a minor fraction (2-5%) of the lung’s internal surface yet play crucial roles. Responsible for producing, secreting, and recycling pulmonary surfactant, they maintain pulmonary fluid equilibrium by regulating active Na+ transport. Beyond these physiological functions, they function as a frontline defense within the lungs, initiating and modulating immune responses during pulmonary infections or allergies. These cells also display regenerative capabilities, acting as progenitors in the distal lung, capable of repairing the epithelium following injury. Notably, in response to pulmonary vaccinia virus infection, they trigger IFN-β and IFN-stimulated genes through MDA5 and STING-mediated nucleic acid-sensing pathways, contributing to immune responses and feedback loops.

 

Why choose C57BL/6 Mouse Type II Alveolar Epithelial Cells from AcceGen?

C57BL/6 Mouse Type II Alveolar Epithelial Cell from AcceGen is a suitable choice for their superior viability and quality. These cells are meticulously maintained under sterile, optimum incubation conditions, backed by stringent quality control measures to ensure consistent and reliable results in your research endeavors.

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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • FOR RESEARCH USE ONLY

  • C57BL/6 Type II Mouse Alveolar Epithelial Cells (AECIIs) are essential tools for in vitro investigations into lung diseases like pulmonary fibrosis and lung injury, offering insights into alveolar epithelium regeneration. With high purity and viability, these cells are suitable for genomic, proteomic analyses, and ex vivo culturing to unravel their contributions across biological processes. They are particularly useful in studying how lung AECIIs’ innate immune sensing safeguards against viral infections, enhancing our understanding of defense mechanisms against pathogens.

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High Viability
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Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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