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C57BL/6 Mouse Thymus Epithelial Cells | ||||
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Product Name | C57BL/6 Mouse Thymus Epithelial Cells | |||
Price | Get Quote | |||
Product Code | MTECs | |||
Cat.No | ABC-TC5502 | Species | C57BL/6 Mouse | |
Size/Quantity | 1 vial | |||
Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
Description | C57BL/6 mouse primary thymus epithelial cells are isolated from the thymus of newborn C57BL/6 mice, which is the most famous inbred mouse strain with reserved genetic basis for cancer research. C57BL/6 has been widely used in biomedical research as either a genetic background or a general purpose strain for spontaneous and induced mutant mice. As the main component of thymic stroma, thymus epithelium cells (TECs) affects T cell development and differentiation through the secretion of the thymic peptides by thymus epithelial cells. The process of T cell development is highly dependent on the communications between the developing T cells and thymus epithelial cells, which especially support the T cell development by providing cytokines, chemokines, lineage inductive ligands, selective self-antigens, cell surface molecules, and extracellular matrix elements.
Why choose C57BL/6 Mouse Primary Thymus Epithelial Cells from AcceGen? AcceGen supports C57BL/6 mouse primary thymus epithelial cells with advanced techniques for primary cells. Our C57BL/6 mouse primary thymus epithelial cell has the best viability and plating efficiency. We guarantee to deliver C57BL/6 mouse primary thymus epithelial cells in a professional, safe, and quick way to ensure that every customer receives the best quality product. | |||
Disease | Normal | |||
Source Organ | Thymus | |||
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
Recommended Medium And Supplement | ABM-TM5502 C57BL/6 Mouse Primary Thymus Epithelial Cells Medium Kit | |||
Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
Application | FOR RESEARCH USE ONLY C57BL/6 mouse primary thymus epithelial cell is a useful cell line to investigate thymic activities, such as the secretion of thymus hormones and the development of thymocytes. Thymus epithelial cells also express MHC class II molecules on the surface, which are involved in the antigen presentation for an immune response. Considering the tight connection with thymocytes, TECs can be used in the research of immune system, such as identification of modulators in thymocyte development. For example, androgen receptor was identified in the immunohistochemical analysis and hormone-binding assay of thymic epithelial cells. C57BL/6 mouse primary thymus epithelial cells can also be used in some interesting trials, such as assessing the resistant to ionizing radiation. | |||
Growth Conditions | 37 ℃, 5% CO2 | |||
Cell Type | Epithelial | |||
Growth Mode | Adherent | |||
Product Type | Mouse Primary Cells | |||
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