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Species | C57BL/6 Mouse |
Cat.No | ABC-TC3212 |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Primary Cells |
Size/Quantity | 1 vial |
Cell Type | Fibroblast |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Lung |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Mouse Primary Cells |
Mouse lung fibroblasts (MLUFC) are isolated from tissue of pathogen-free laboratory mice. Mouse lung fibroblasts are grown in T75 tissue culture flasks pre-coated with 0.2% gelatin for 0.5 hour and incubated in Culture Complete Growth Medium generally for 3-7 days.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
For research use only
C57BL/6 Mouse Lung Fibroblasts are specialized fibroblast cells derived from the lung tissue of C57BL/6 mice. They play a key role in maintaining the structural integrity of lung tissue by producing extracellular matrix proteins and supporting the repair and remodeling processes in response to injury.
The main functions of these fibroblasts include synthesizing extracellular matrix components like collagen and elastin, which maintain lung tissue architecture. They also play a significant role in wound healing, fibrosis, and lung tissue repair, especially after injury or inflammation.
In pulmonary fibrosis, these fibroblasts become activated and differentiate into myofibroblasts, which produce an excess of extracellular matrix proteins. This leads to scarring or fibrosis in the lung, resulting in impaired respiratory function and lung stiffness.
These cells are utilized in research focused on lung tissue repair, fibrosis, inflammation, and wound healing. They are also used in drug discovery for developing therapies targeting lung diseases, including treatments aimed at reducing fibrotic tissue formation.