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C57BL/6 Mouse Liver Kupffer Cells

Product Name

C57BL/6 Mouse Liver Kupffer Cells

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Cat.No

ABC-TC5523

Species

C57BL/6 Mouse

Size/Quantity

1 vial

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

C57BL/6 Mouse Liver Kupffer Cells are specialized macrophages located in the liver, derived from the C57BL/6 mouse strain. These cells play a critical role in the immune response by clearing pathogens, dead cells, and debris from the blood. Kupffer cells are pivotal in maintaining liver homeostasis and mediating inflammatory responses during liver injury or infection. They are extensively used in research to study liver function, immune responses, and the mechanisms underlying liver diseases. Isolated from the genetically well-characterized C57BL/6 strain, these cells offer consistency and reliability for various experimental applications, including immunology, toxicology, and liver disease modeling. Each vial contains > 1 × 106 cells in 1mL volume.

Disease

Normal

Source Organ

Liver

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

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Application

For research use only

Growth Conditions

37 ℃, 5% CO2

Cell Type

Kupffer Cell

Growth Mode

Suspension

Product Type

Mouse Primary Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial

Frequently Asked Questions

  • What are the primary functions of Kupffer cells in the liver?

    Kupffer cells are specialized macrophages that play a key role in immune defense and the removal of pathogens and debris from the liver.

  • Why are C57BL/6 mice commonly used for isolating Kupffer cells?

    C57BL/6 mice are widely used due to their well-characterized immune system and genetic background, making them ideal for immunological studies.

  • What are the recommended culture conditions for C57BL/6 Mouse Liver Kupffer Cells?

    Kupffer cells should be cultured in a suitable medium supplemented with growth factors like M-CSF and maintained at 37°C with 5% CO2.

  • Can C57BL/6 Mouse Liver Kupffer Cells be used in inflammation and liver disease models?

    Yes, these cells are frequently used in studies related to liver inflammation, fibrosis, and other liver diseases to understand macrophage roles.

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