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C57BL/6 Mouse Liver Kupffer Cells

  • BSL
  • 54
C57BL/6 Mouse Liver Kupffer Cells are derived from the liver of pathogen-free laboratory adult mice. Cells are grown in tissue culture flasks and incubated in AcceGen’s Cell Culture Medium for 2-5 days. Prior to shipping, cells at passage 0 are detached from flasks and cryopreserved in vials. Each vial contains 3 x10^6cells and is delivered […]
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | C57BL/6 Mouse Liver Kupffer Cells

C57BL/6 Mouse Liver Kupffer Cells are specialized macrophages located in the liver, derived from the C57BL/6 mouse strain. These cells play a critical role in the immune response by clearing pathogens, dead cells, and debris from the blood. Kupffer cells are pivotal in maintaining liver homeostasis and mediating inflammatory responses during liver injury or infection. They are extensively used in research to study liver function, immune responses, and the mechanisms underlying liver diseases. Isolated from the genetically well-characterized C57BL/6 strain, these cells offer consistency and reliability for various experimental applications, including immunology, toxicology, and liver disease modeling. Each vial contains > 1 × 106 cells in 1mL volume.

Species

C57BL/6 Mouse
Cat.No

ABC-TC5523
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Kupffer Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

Frequently Asked Questions

  • What are the primary functions of Kupffer cells in the liver?

    Kupffer cells are specialized macrophages that play a key role in immune defense and the removal of pathogens and debris from the liver.

  • Why are C57BL/6 mice commonly used for isolating Kupffer cells?

    C57BL/6 mice are widely used due to their well-characterized immune system and genetic background, making them ideal for immunological studies.

  • What are the recommended culture conditions for C57BL/6 Mouse Liver Kupffer Cells?

    Kupffer cells should be cultured in a suitable medium supplemented with growth factors like M-CSF and maintained at 37°C with 5% CO2.

  • Can C57BL/6 Mouse Liver Kupffer Cells be used in inflammation and liver disease models?

    Yes, these cells are frequently used in studies related to liver inflammation, fibrosis, and other liver diseases to understand macrophage roles.

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  • Liver (143)
  • Mouse (639)
  • Normal (1578)

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