C57 Mouse Cortex Neurons

Frequently Asked Questions

• What is C57 Mouse Cortex Neurons?

  C57 Mouse Cortex Neurons are neurons isolated from the cortex of C57BL/6 mice, characterized by their ability to maintain electrophysiological properties and morphological features in vitro, making them valuable for detailed cellular and molecular studies.

• Application of C57 Mouse Cortex Neurons

  C57 Mouse Cortex Neurons are utilized in experiments to study brain function, neurodevelopment, and neurological diseases. These neurons are essential for research in synaptic plasticity, neuropharmacology, electrophysiology, and neurotoxicity. They enable scientists to investigate the mechanisms underlying learning and memory, evaluate the effects of drugs on neuronal activity, and explore the cellular responses to toxic insults. Additionally, they provide valuable insights into the pathophysiology of neurodegenerative diseases like Alzheimer’s and Parkinson’s, aiding in the development of potential therapeutic interventions.

• What is the growth and morphology of C57 Mouse Cortex Neurons?

  Medium: ABM-TM3919 C57 Mouse Cortex Neurons Medium Kit

  C57 Mouse Cortex Neurons exhibit a complex morphology with extensive dendritic and axonal arborization, typical of cortical neurons. They grow in vitro on poly-D-lysine or laminin-coated surfaces, requiring a neurobasal medium supplemented with B27, glutamine, and growth factors. These neurons typically form synaptic connections and display spontaneous electrical activity, making them ideal for studying neuronal connectivity and function. Optimal growth conditions include maintaining at 37oC in a humidified atmosphere with 5% CO2.