BPAEC
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The Bovine Pulmonary Artery Endothelial (BPAE) cell line is derived from the main stem of the pulmonary artery in young Bos taurus (cows). These arteries, unique in their function of transporting unoxygenated blood from the heart to the lungs, serve as the source material for cultivating BPAE cells. Notably, BPAE cells exhibit positivity for bovine diarrhea virus, a prominent pathogen in cattle responsible for a range of clinical syndromes leading to significant economic losses within the beef industry. Additionally, these cells express angiotensin converting enzyme (ACE), a pivotal enzyme involved in the intricate regulation of blood pressure and volume. As such, the BPAE cell line serves as a valuable tool for scientific investigations into vascular physiology and viral pathogenesis.
Why choose BPAEC from AcceGen?
BPAEC (Bovine Pulmonary Artery Endothelial Cells) from AcceGen are characterized by their exceptional quality and high viability. These cells are cryopreserved at the second passage, with each vial containing over 0.5×106 cells, ensuring an ample and reliable supply. They exhibit robust growth potential, capable of undergoing at least 16 doublings, and undergo rigorous quality control measures to maintain consistency and reliability in research applications.
| Product Code | Bovine Pulmonary Artery Endothelial Cells; BPAE |
| Species | Bos Taurus |
| Cat.No | ABC-TC0080 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Endothelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Bovine Lung Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The Bovine Pulmonary Artery Endothelial (BPAE) cell line serves as a pivotal resource in the realm of cardiovascular research, offering a robust model system to explore multifaceted aspects of cardiovascular function and pathology. Particularly pertinent to hypertension, atherosclerosis, and coronary heart disease investigations, BPAE cells are instrumental in deciphering intricate signaling pathways and mechanisms governing endothelial functionality. Their utility extends to studies involving angiogenesis, vascular permeability, and nitric oxide (NO) production. Moreover, BPAE cells prove invaluable in scrutinizing diabetes-related cardiovascular complications, elucidating the intricacies of endothelial dysfunction induced by environmental pollutants, smoking, oxidative stress, and inflammation, and uncovering potential therapeutic interventions. Additionally, they facilitate the development of advanced co-culture models, such as liver-endothelial systems, distinguished by their capacity to exhibit superior liver-specific attributes, enhancing our capacity for specialized research endeavors.
