Bovine muscle satellite cells are AcceGen’s bovine primary cell products isolated from the longissimus muscle of calves. Satellite cells are the myogenic progenitor cells in the skeletal muscle of postnatal animals, and are essential to the regeneration and growth of skeletal muscle. Therefore, they are commonly referred to as skeletal muscle satellite cells. When muscle is injured, muscle satellite cells are transformed from a normally quiescent form to activated cells, which can increase muscle size by proliferation as myoblasts, differentiation, and the fusion with muscle fibers or with each other to generate muscle fibers. Bovine skeletal muscle satellite cells are cultured in the DMEM medium supplemented with 10% FBS, 2mM L-glutamine, and 1% antibiotics-antimycotics, and trypsin-EDTA (0.25%) can be used for their detachment.
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