BeWo Clone b30
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The BeWo choriocarcinoma cell line, specifically the b30 clone, is a human trophoblast cell line that exhibits notable morphological and biochemical differentiation, which closely mirrors the characteristics observed in normal trophoblasts. This differentiation process is initiated through the elevation of intracellular cAMP levels when exposed to forskolin, effectively emulating the regulatory mechanisms of normal trophoblasts. Importantly, BeWo clone b30 cells have been demonstrated to express neutral amino acid transport systems that closely resemble those found in their normal trophoblast counterparts, with similar contributions from systems A, ASC, and L.
Why choose BeWo Clone b30 from AcceGen?
BeWo Clone b30 boasts exceptional characteristics, including high viability and quality, ensured sterility with negative results for bacteria, yeast, mycoplasma, as well as absence of human pathogens like HIV, HBV, and HCV. Its identity is rigorously confirmed through STR analysis, ensuring stringent quality control in research applications.
| Product Code | BeWo clone b30; BeWo cells subclone b30 |
| Species | Human |
| Cat.No | ABC-TC535S |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Choriocarcinoma |
| Disease | Choriocarcinoma |
| Storage | Liquid Nitrogen |
| Product Type | Human Germ Cell Cancer Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
BeWo Clone b30 finds extensive applications as a crucial model for exploring trophoblast behavior and physiological functions in diverse research domains. Its utility is particularly pronounced in transport studies due to the formation of polarized, confluent monolayers, making it a valuable in vitro representation of the rate-limiting barrier to maternal-fetal exchange. Researchers have harnessed this choriocarcinoma cell line not only for investigating various transport mechanisms but also to delve into the intricacies of placental metabolism, shedding light on critical aspects of maternal-fetal health and development.
