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| Product Code | BEWO; Be Wo; Be-Wo |
| Species | Human |
| Cat.No | ABL-TC0104 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Placenta |
| Disease | Choriocarcinoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Uterine Cancer Cell Lines |
BeWo cells constitute a cell line originating from malignant gestational choriocarcinoma of the fetal male placenta. They exhibit an epithelial-like phenotype and grow in an adherent monolayer fashion. These cells are characterized by the expression of molecular markers such as CK 7, E-cadherin, and VE-cadherin, with the latter showing enhanced expression following forskolin treatment. Additionally, BeWo cells express keratin and exhibit positivity for G6PD and B isoenzyme. Notably, these cells are prolific hormone secretors, producing human chorionic gonadotropin (hCG), human chorionic somatomammotropin (placental lactogen), and various steroid hormones including estrone, estriol, and estradiol.
Why choose BeWo from AcceGen?
BeWo cells from AcceGen are distinguished by their exceptional quality, boasting high viability due to expert cryopreservation. These cells are maintained under stringent sterility conditions, with continuous monitoring to guarantee freedom from bacterial and fungal contaminants. Furthermore, PCR-based analysis ensures mycoplasma-free status, and the cells’ identity is confirmed through STR analysis.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
BeWo cells hold substantial utility in elucidating the intricate processes that govern placental development. Of particular significance is the phenomenon of cell-cell fusion during the human trophoblast syncytialization phase, a critical yet poorly understood event in placental development. Due to the inherent challenges associated with in vivo studies of this process in the placenta, BeWo cells emerge as an indispensable in vitro model for replicating the in vivo syncytialization of the placental villous trophoblast, facilitating controlled and detailed investigations into this complex phenomenon.
