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Tumor Cell Lines

Beta-TC-6

  • BSL

    1

  • 136
The cell line was derived from a pancreatic tumor (RIoma) arising in a transgenic mouse. The mouse carried the pseudogene construct composed of the SV40 early region controlled by the rat RI II gene promotor. The cells contain abundant insuli.
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The Beta-TC-6 cell line originates from a transgenic mouse-derived pancreatic insulinoma and possesses a unique genetic profile characterized by the incorporation of the SV40 early region controlled by the rat insulin gene promoter. This distinctive genetic configuration endows Beta-TC-6 cells with the ability to secrete insulin in a glucose-responsive manner. Morphologically, these cells exhibit an epithelial phenotype, predominantly localizing within pancreatic tissue. In addition to insulin, they exhibit modest production of glucagon and somatostatin. Notably, their strong adherence characteristics render Beta-TC-6 cells highly amenable for cultivation and manipulation in experimental and assay settings, rendering them a valuable asset in diabetes and 2pancreatic research endeavors.

 

Why choose Beta-TC-6 from AcceGen?

Beta-TC-6 cells from AcceGen exhibit exceptional features, boasting high viability and quality. They are meticulously incubated under optimal conditions to ensure their vitality. Moreover, these cells undergo rigorous quality control procedures, including sterility assessments, daily visual monitoring for the absence of bacterial and fungal contaminants, guaranteeing their reliability for scientific research.

Product Code

beta-TC-6; beta-TC6; beta TC6; BetaTC6; betaTC6

Species

Mouse

Cat.No

ABC-TC0074

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Disease

Insulinoma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Pancreas Cancer Cell Lines

Citation

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Application

  • FOR RESEARCH USE ONLY

  • The Beta-TC-6 cell line plays a pivotal role in advancing scientific inquiries within the domains of diabetes and insulin signaling. Its distinctive genetic profile, capacity for insulin secretion, and robust adhesion properties render it an invaluable tool for delving into the complex intricacies of glucose regulation and pancreatic functionality. Consequently, it enables the elucidation of fundamental physiological processes underlying diabetes pathogenesis and holds promise for informing the development of novel therapeutic interventions.

Inquiring Beta-TC-6

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High Viability
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Customization Options
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Tags

  • Epithelial (292)
  • Mouse (639)
  • Pancreas (43)
  • Pancreas Cancer (28)
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