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Transfected Stable Cell Lines

BCL10 Knockout Cell Lysate

  • BSL
  • 114
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 […]
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This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Species

Human

Cat.No

ABC-KC0187

Product Category Transfected Stable Cell Lines
Size/Quantity

100ug

Shipping Info

Ice Pack

Growth Conditions

37 ℃, 5% CO2

Storage

Store BCL10 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.

Product Type

CRISPR Knockout Cell Lysate

Host Cell

HeLa

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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Application

  • For research use only

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