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BALL-1

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Product Name

BALL-1

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Product Code

Ball-1; Ball 1; BALL1; B-cell Acute Lymphoblastic Leukemia-1

Cat.No

ABC-TC0069

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The BALL-1 cell line is a human B-cell line derived from the peripheral blood of an acute lymphoblastic leukemia (ALL) patient. It exhibits unique characteristics, including its ability to induce T cells to produce a distinctive eosinophil chemotactic factor. Transplantation into immunodeficient hamsters results in aggressive infiltration of skin and bone marrow, rapid tumor growth, and eventual leukemia development. BALL-1 cells are susceptible to the cytotoxic effects of the lectin Abrin-a, while the protein GPSM1 promotes tumor growth within the cell line. Cultures can be sustained through fresh medium supplementation or by subcultivation through centrifugation and subsequent resuspension at a 1:2-1:4 ratio.

 

Why choose BALL-1 from AcceGen?

The BALL-1 cell line exhibits robust viability and quality, maintaining sterility by testing negative for bacteria, fungi, and mycoplasma contamination. Its identity is confirmed through STR profiling, ensuring accurate characterization and validation.

Disease

Acute Lymphoblastic Leukemia

Source Organ

Peripheral Blood

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The BALL-1 cell line emerges as a vital resource in immunological research and the advancement of precise treatments for acute lymphoblastic leukemia. Its relevance extends to serving as a model for pinpointing novel therapeutic targets within this context. By leveraging its unique characteristics, researchers can potentially formulate inhibitors or drugs that effectively differentiate human leukemic cells, thus holding promise for both laboratory investigations and future clinical applications.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Lymphocyte-like

Product Type

Human Leukemia Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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