B16-F10
1
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The B16-F10 cell line, a murine melanoma B16 subline, originates from C57BL/6J mouse skin tissue. Displaying a distinctive spindle-shaped, epithelial-like morphology, these cells were isolated based on their remarkable ability to generate lung colonies following intravenous injection. This unique trait was honed through 10 cycles of lung colony formation, culminating in their establishment in vitro. With a doubling time of approximately 20.1 hours, B16-F10 cells showcase an impressive propensity for lung metastasis. Notably, when introduced into mouse skin, these cells exhibit a noteworthy perivascular predominance in VEGF expression across numerous vessels.
Why choose B16-F10 from AcceGen?
The B16-F10 cell line boasts robust viability and quality, upheld under sterile conditions and verified negative for bacterial, fungal, and mycoplasma contamination. Maintained in optimal incubation conditions, its excellence is ensured through stringent quality control measures.
| Product Code | B16/F10; B16 F10; B16F10; B16 melanoma F10 |
| Species | Mouse |
| Cat.No | ABC-TC0062 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Skin |
| Disease | Melanoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Melanoma Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The B16-F10 cell line holds a pivotal role in advancing skin cancer research, with a specific emphasis on the intricate realm of metastasis. Their distinctive profile, marked by low immunogenicity and remarkable aggressiveness, positions them as a cornerstone in studies related to murine tumor immunotherapy. Furthermore, they serve as a crucial tool for deciphering the complex factors governing the successful implantation and subsequent survival of B16 melanoma. Moreover, these cells provide a reliable platform for evaluating the inhibitory effects of various agents on murine melanoma metastasis, allowing for a comprehensive understanding of the underlying mechanisms at play.
