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Transfected Stable Cell Lines

AXIN1 Knockout Cell Lysate

  • BSL
  • 101
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site […]
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This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Species

Human

Cat.No

ABC-KC0166

Product Category Transfected Stable Cell Lines
Size/Quantity

100ug

Shipping Info

Ice Pack

Growth Conditions

37 ℃, 5% CO2

Storage

Store AXIN1 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.

Product Type

CRISPR Knockout Cell Lysate

Host Cell

HeLa

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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Application

  • For research use only

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