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Transfected Stable Cell Lines

AMACR Knockout Cell Lysate

  • BSL
  • 76
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, […]
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This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]

Species

Human

Cat.No

ABC-KC0071

Product Category Transfected Stable Cell Lines
Size/Quantity

100ug

Shipping Info

Ice Pack

Growth Conditions

37 ℃, 5% CO2

Storage

Store AMACR KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.

Product Type

CRISPR Knockout Cell Lysate

Host Cell

HeLa

Citation

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Application

  • For research use only

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