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Transfected Stable Cell Lines

ALK Knockout Cell Lysate

  • BSL
  • 94
This gene encodes a receptor tyrosine kinase, which belongs to the RI receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the […]
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This gene encodes a receptor tyrosine kinase, which belongs to the RI receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).[provided by RefSeq, Jan 2011]

Species

Human

Cat.No

ABC-KC0067

Product Category Transfected Stable Cell Lines
Size/Quantity

100ug

Shipping Info

Ice Pack

Growth Conditions

37 ℃, 5% CO2

Storage

Store ALK KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.

Product Type

CRISPR Knockout Cell Lysate

Host Cell

HeLa

Citation

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Application

  • For research use only

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