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Knockout Stable Cell Lines
The CRISPR/Cas9 system has been developed as the most popular method for genome editing in recent years. The engineered CRISPR/Cas9 technology consists of a single guide RNA (sgRNA) and a human codon optimized Cas9 nuclease. The sgRNA recognizes the genomic target via standard Watson–crick base pairing and acts as a scaffold for binding of the endonuclease Cas9. Then Cas9 protein introduces site-specific DSBs in the target DNA sequences. Besides, in the phase of target recognition, the protospacer adjacent motif (PAM) adjacent to the 3’ end of the DNA target site is indispensable. Finally, targeted mutations can be induced by nonhomologous end joining (NHEJ).
CRISPR-Cas9 is a genome-editing tool that is creating a buzz in the science world. It is faster, cheaper and more accurate than previous techniques of editing DNA and has a wide range of potential applications. Our scientists use the CRISPR CAS9 (CRISPR/Cas9) to knock out one or double genes to generate a KO cell line.
AcceGen is offering a series of gene knockout cell lines developed by the CRISPR/Cas9 system. These cell lines provide you with a convenient means to study gene functions. Use the Mutant Gene Nomenclature to search, if you cannot find the specific product in our database, AcceGen Custom Stable Cell Lines Service is committed to pave new ways to meet all your needs.
Cat.# | Name | Description | Stock | Price |
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ABC-KH17977 | Human ESR1 Mutant cell line | ESR1 Mutant cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17976 | Human VHL knockout cell line | Human VHL knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17975 | Green Monkey NECTIN1 knockout cell line | Green Monkey NECTIN1 knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17974 | Human AP1S1 knockout cell line | Human AP1S1 knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17973 | Human SNORA59B knockout cell line | Human SNORA59B knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17972 | Human SMG6 knockout cell line | Human SMG6 knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17971 | Pig KLF4 knockout cell line | Pig KLF4 knockout cell line is edited by CRISPR/Cas9 technology. ...more | Custom | +inquiry |
ABC-KH17970 | Rat KLF4 knockout cell line | Rat KLF4 knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17969 | Mouse CD115 knockout cell line | Mouse CD115 knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17968 | Mouse IL17RA knockout cell line | Mouse IL17RA knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17967 | Mouse TUT1 knockout cell line | Mouse TUT1 knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17966 | Mouse AK2 knockout cell line | Mouse AK2 knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17965 | Human TING knockout cell line | Human TING knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17964 | Human LOC100270804 knockout cell line | Human LOC100270804 knockout cell line is edited by CRISPR/Cas9 technology. ...more | Custom | +inquiry |
ABC-KH17963 | Human IL17RA knockout cell line | Human IL17RA knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17962 | Human LINC00944 knockout cell line | Human LINC00944 knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17961 | Human RAPSYN knockout cell line | Human RAPSYN knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17960 | Human BRCA2 knockout cell line | Human BRCA2 knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17959 | Human TANGO6 knockout cell line | Human TANGO6 knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |
ABC-KH17958 | Human BRCA2 knockout cell line | Human BRCA2 knockout cell line is edited by CRISPR/Cas9 technology. ...more | In Stock | +inquiry |