RC-K8
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The RC-K8 cell line is a human cell line derived from the peritoneal effusion of a patient with histiocytic lymphoma. Characterized by a pleomorphic morphology, RC-K8 cells primarily grow in a single cell suspension. They exhibit positive reactions for alpha-naphthyl butyrate esterase, acid phosphatase, and periodic acid-Schiff stainings, indicating their biochemical properties. Immunologically, RC-K8 cells are reactive to monoclonal antibodies targeting B cell antigens (B1 and Leu12) and Ia antigen (OKIa1), and they show immunoglobulin gene rearrangement despite the absence of surface and cytoplasmic immunoglobulin. Chromosomal analysis reveals complex abnormalities, including a translocation involving chromosomes 11 and 14.
Why choose RC-K8 from AcceGen?
RC-K8 cell line from AcceGen offers key advantages. Our well-equipped lab and professional technicians ensure regular maintenance, keeping the cells in optimal condition. We implement rigorous quality control to guarantee mycoplasma-free status and conduct STR identification for authenticity. With these measures, you can trust that RC-K8 is reliable and well-suited for your research needs.
| Product Code | RCK-8; RCK8; Rck8 |
| Species | Human |
| Cat.No | ABL-TC0580 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Peritoneal Effusion |
| Disease | Malignant Lymphoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lymphoma Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The RC-K8 cell line is invaluable for studying lymphomagenesis and pulmonary metastasis in lymphoma. It serves as a model for investigating the antitumor effects of potential drugs, particularly those targeting B-cell lymphoma. Researchers utilize RC-K8 to explore immunotherapy strategies for lymphoma, focusing on key enzymes involved in immune evasion. Additionally, this cell line is pivotal in drug discovery, aiding in the evaluation of novel compounds’ antitumor activity and elucidating their molecular mechanisms against hematopoietic malignancies.
