DMS 153
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The DMS 153 cell line was derived from metastatic liver tissue obtained during autopsy from a patient afflicted with small cell carcinoma of the lung (SCLC) who had undergone cytoxan and methotrexate treatment. These cells exhibit tumorigenic properties in nude mice and secrete moderate amounts of calcitonin (CT) and calcitonin gene-related peptide (CGRP). Furthermore, they have been found to produce adrenocorticotropin (ACTH), bombesin (BN), 17 beta-estradiol, and oxytocin-neurophysin (OT-NP). DMS 153 cells express various cell surface antigens, including Leu 7, HLA-DR, My 23, the AML-1-99 defined antigen, and CR3 receptor, while also possessing receptors for bombesin (BN) and epidermal growth factor (EGF).
Why choose DMS 153 from AcceGen?
AcceGen’s DMS 153 cell line stands out for its robust features, boasting high viability and top-notch quality. These cells are carefully nurtured under ideal conditions and expertly cryopreserved. They are delivered in a sterile state, thoroughly screened to be mycoplasma-free, and their identity is confirmed through STR analysis, all part of AcceGen’s stringent quality control measures, making them a trusted and reliable choice for research applications.
| Product Code | DMS-153; DMS153 |
| Species | Human |
| Cat.No | ABC-TC0213 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Disease | Lung Small Cell Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lung Cancer Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The DMS 153 cell line plays a pivotal role in cancer research, particularly in the study of small cell carcinoma of the lung (SCLC). Researchers utilize this cell line to identify novel biomarkers that can aid in the diagnosis and treatment of SCLC. Additionally, DMS 153 cells are instrumental in elucidating the effects of potential therapeutic strategies on cancer cells, including the induction of apoptosis, offering valuable insights into the development of more effective treatments for this aggressive form of lung cancer.
